en ویروس شناسی Virology Research Article Research Article <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Times New Roman;"><b>Background:</b> Human papillomaviruses (HPVs) are DNA viruses from the <i>Papillomaviridae</i> family. These viruses are linked to about 5% of human cancers, with a significant association with cervical cancer. Infection with this virus can be screened in women to prevent cervical cancer.<br> <b>Methods:</b> This review analyzes articles published over the last two decades regarding self-sampling, papillomavirus, and cervical cancer. The search for articles was conducted using various scientific databases, with selections based on their relevance to the topic and their contribution to understanding and comparing methods. Key results were examined, focusing on social aspects, economic savings, and participants&#39; satisfaction with the self-sampling method.<br> <b>Results:</b> One of the most common and effective methods for HPV screening is sampling from the cervix using the Pap smear method and molecular techniques, widely used in various countries. Currently, HPV screening methods in different countries are primarily limited to clinical sampling, which cannot cover all urban and rural populations. The World Health Organization has recommended and supported self-sampling for HPV screening as a new strategy.<br> <b>Conclusion</b>: This mini-review discusses the self-sampling method for HPV screening, its advantages, and its application in different countries. As self-sampling can address the needs of both rural and urban areas, it is more economically viable and helps minimize cultural barriers and public opinion challenges compared to clinical sampling. The HPV self-sampling strategy offers an effective and efficient method for HPV screening, aiming to cervical cancer caused by the HPV virus in various countries.</span></span></div> Self-sampling for cervical cancer screening 32 35 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1825-1&slc_lang=en&sid=1 Sedigheh Damavandi Kamali elnazkamalidm@gmail.com 100319475328460029425 0009-0002-5825-1833 No Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran Iliad Moradi sarasemnani22@gmail.com 100319475328460029426 0009-0000-9784-1444 No Department of Laboratory Sciences, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran Abdolvahab Moradi abmoradi@gmail.com 100319475328460029427 100319475328460029427 Yes Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran