fa تحقيقي Original Paper <div> <p><strong>ABSTRACT</strong></p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Background and Objective</strong>: The association of Triglyceride/High Density Lipoprotein-Cholesterol (TG/HDL-C) ratio with fasting serum insulin, which is an alternative method of insulin resistance (IR) measurement, is well-recognized. Thus, the measurement of TG/HDL-C ratio is useful to determine both IR and dyslipidemia, which itself is a characteristic of individuals with IR. Therefore, this study aimed to investigate the relationship between TG/HDL ratio as an indicator of IR, with different fasting blood glucose levels.</p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Methods</strong>: This case-control study was performed on 343 volunteers with no history of diabetes or use of blood glucose-lowering medications and fasting blood sugar (FBS) levels of less than 126 mg/dl. After sampling, the subjects were divided into three groups based on their FBS level. First group included healthy subjects with FBS of less than 100 mg/dl. Second group consisted of subjects with impaired fasting glucose (IFG) and FBS of 110-100 mg/dl and a third group including those with impaired glucose tolerance (IGT) and FBS of 110-125 mg/dl.</p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Results</strong>: The amount of TG/HDL-C ratio was 3.8 &plusmn; 2.8, 4.0 &plusmn; 2.1 and 5.4 &plusmn; 3.8 for the healthy group, individuals with IFG and IGT, respectively. The TG/HDL index was significantly different among the tested groups with no significant difference between healthy subjects and subjects with IFG. Moreover, there was a statistically significant difference between the IGT and IFG groups with healthy individuals.</p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Conclusion</strong>: Considering the significant increase of the TG/HDL ratio in groups with impaired glucose, using this index can be helpful in evaluation of glycemic disorder.</p> <p><strong>&nbsp;&nbsp; </strong></p> </div> Insulin resistance, fasting blood glucose, impaired glucose tolerance, impaired fasting glucose, TG/HDL ratio. 50 55 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-384&slc_lang=fa&sid=1 Maryam MoradiBinabaj 100319475328460010874 100319475328460010874 Yes Golestan University of Medical Sciences, Gorgan, Iran Mohadese Namjoo 100319475328460010875 100319475328460010875 No Medical Laboratory Research Center, Golestan University of Medical Sciences, Gorgan, Iran Mojgan Nejabat 100319475328460010876 100319475328460010876 No Medical Laboratory Research Center, Golestan University of Medical Sciences, Gorgan, Iran Hamidreza Joshaghani 100319475328460010877 100319475328460010877 No Medical Laboratory Research Center, Golestan University of Medical Sciences, Gorgan, Iran