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Showing 2 results for Kalhan
Evaluating Association between ABO Blood Groups and COVID 19
Bhumika Gupta, Shivani Kalhan, Shalini Shukla, Shalini Bahadur, Gyanendra Singh, Rambha Pathak,
Volume 15, Issue 6 (Special issue (Nov-Dec) 2021)
Abstract
Introduction: COVID 19 pandemic caused by SARS-COV2 virus has taken a toll all over the world. The susceptibility of various diseases like Helicobacter Pylori, Hepatitis B virus and Norwalk Virus and even SARS Corona Virus 1 have been associated with ABO blood groups. However, very limited data is available regarding the COVID 19 susceptibility and ABO blood groups. Methods: In the present report we investigated 500 admitted patients who were RTPCR positive for corona virus. Significant Tests were applied to study association of blood groups vis a vis disease severity, ICU admissions and assisted ventilation. Results:  We found out that Type A blood group is more susceptible to severe COVID 19 infection, even though maximum patients were of type B blood group. We also found that type A blood group needed more ICU admission and assisted ventilation then non type A groups and difference was statistically significant. Conclusion: Patients with type A blood group COVID 19 patients with type A blood group might require more vigilant surveillance and aggressive treatment measures. Further studies are required to validate the disease susceptibility.
Papillary thyroid carcinoma in cervical lymph node found in a patient of primary tongue squamous cell carcinoma: Ectopic thyroid versus metastatic deposits; A diagnostic dilemma
Paridhi ., Shalini Bahadur , Bhuvan Adhlakha , Shivani Kalhan , Hukam Singh ,
Volume 20, Issue 1 (Jan-Feb 2026)
Abstract
Background: The incidental discovery of papillary thyroid carcinoma (PTC) in cervical lymph nodes during neck dissection for tongue squamous cell carcinoma (SCC) is an exceedingly rare finding, reported in approximately 0.3 - 1.6% of head and neck squamous cell carcinoma (HNSCC) cases. Differentiating between metastatic PTC and papillary carcinoma arising in aberrant thyroid tissue poses a diagnostic challenge, especially in the absence of a detectable thyroid mass.
Case Presentation: A 35-year-old male presented with a rapidly growing ulcero-proliferative lesion on the lateral border of the tongue for four months. Biopsy revealed moderately differentiated SCC. The patient underwent hemiglossectomy with supraomohyoid neck dissection. Histopathology confirmed SCC with clear margins and no nodal metastasis; however, one cervical lymph node revealed thyroid follicles with cells showing optically clear nuclei. Immunohistochemistry was positive for TTF1 and HBME-1, confirming metastatic PTC. No palpable thyroid nodule was identified, and computed tomography demonstrated only hypodense colloid nodules. Thyroid function tests were normal, and the patient remains disease-free on follow-up without thyroid surgery.
Conclusion: The coexistence of tongue SCC and metastatic PTC in cervical lymph nodes is exceptionally uncommon. The absence of a primary thyroid lesion raises questions regarding the origin - occult metastasis versus transformation in aberrant thyroid tissue. The literature supports conservative management with vigilant follow-up when thyroid imaging shows no evidence of malignancy. Meticulous histopathological examination of neck dissection specimens in HNSCC is vital. Management should be individualized, balancing surgical intervention and surveillance based on clinic radiologic findings.
 

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