Search published articles


Showing 3 results for Fever
Abnormal Paraclinical Findings of the Neonates with Fever Admitted to the Neonantal Ward of Amir-KabirHospital, Arak City in 2011
, , , ,
Volume 7, Issue 2 (7-2013)
Abstract
Abstract Background and Objective: The vast clinical testing process often is performed to diagnose the origin of the fever. The aim of this study was to investigate the rate of abnormal paraclinical findings of the neonates with fever. Material and methods: This cross-sectional study was carried out on 109 randomly selected febrile neonates admitted to Amir-Kabir Hospital, 2010. Blood, Cerebro Spinal Fluid (CSF) and Urine samples were sent to laboratory and the results were analyzed by Chi-Square test, using SPSS software. Results: Blood culture of 19 cases (17.43 %) is positive. None of the CSF samples are gram positive and also show the sign of Meningitis. Conclusion: With regard to the high rate of positive blood culture, it seems that the use of blood culture in febrile neonates is important for diagnosis. Keywords: Fever Neonate Paraclinical Test
Prevalence of Coxiella burnetii in Bulk Tank Milk Samples from Dairy Cattle in West and Northwest of Iran
Arvin Shajeie, Mohammad Khalili, Zeinab Abiri, Sajad Akbari,
Volume 11, Issue 1 (1-2017)
Abstract
ABSTRACT
       Background and Objectives: Q fever is a zoonotic disease caused by an obligate gram-negative intracellular pathogen called Coxiella burnetii. The aim of this study was to determine the seroprevalence of anti-C. burnetii antibodies in bulk tank milk (BTM) samples of dairy cattle in west and northwest of Iran.
       Methods: Overall, 71 BTM samples (covering nearly 700 dairy cattle) were collected in autumn 2013. A commercial Q fever antibody ELISA Test Kit (Liebefeld-Bern, Switzerland) was used to identify the presence of antibodies against inactivated phase 1 and phase 2 C. burnetii antigens.
       Results: The results of ELISA test showed that 17 BTM samples (23.9%) were positive for the presence of anti-C. burnetii antibodies.
       Conclusion: This study is the first to evaluate presence of anti-C. burnetii antibodies in BTM samples from dairy cattle herds in west and northwest of Iran. The high prevalence of this pathogen highlights the need for pasteurization of raw milk and raising awareness in consumers of dairy products in these regions.
           Keywords: Q fever, Cattle, Iran, Coxiella.

Comparison of antityphoidal efficacy of Moringa oleifera seed oil to antibiotics against Salmonella typhi
Sikiru Kayode Abdulahi ,
Volume 20, Issue 1 (1-2026)
Abstract
Background: Typhoid fever, a severe febrile illness prevalent in tropical regions, remains a significant cause of mortality. Drug-resistant pathogens have spurred research into medicinal plants as alternative treatments. While previous studies have focused on the inhibitory effects of Moringa oleifera leaf extract, limited attention has been given to M. oleifera seed oil and its effects on Gram-negative bacteria. This study aimed to evaluate the anti-typhoidal activity of M. oleifera seed oil against both typed and clinical Salmonella typhi isolates.
Methods: The anti-typhoidal activity of M. oleifera seed oil was assessed using agar diffusion and disk diffusion methods. Phytochemical screening of the seed oil was also conducted to identify its constituents.
Results: M. oleifera seed oil exhibited negligible or weak inhibitory effects on clinical and typed S. typhi strains (p>0.05), in contrast to the substantial inhibition observed with commercial antibiotics. Ciprofloxacin demonstrated the highest zones of inhibition (≥30 mm) against S. typhi, while tetracycline showed the least pronounced inhibition (≤16 mm). Phytochemical screening of M. oleifera seed oil identified terpenoids, cardiac glycosides, saponins, tannins, and flavonoids, with terpenoids being the most abundant and flavonoids the least abundant.
Conclusion: M. oleifera seed oil lacks significant therapeutic potential for the treatment of typhoid fever. Its antibacterial constituents are minimal or absent, resulting in insignificant inhibition against S. typhi.

Page 1 from 1